cancer

The observation helps explain why, as people age, the prostate tends to grow, leading to an increased risk for cancer and other conditions.

Research brief: The study recommends that the new procedure should become the standard of care.

The researchers' study builds on their discovery last year of a gene called mEAK-7, which is important for cell proliferation and migration.

The discoveries by an interdisciplinary team of UCLA scientists could improve the diagnoses of these aggressive cancers.

Research Brief: An increase in the state's HPV vaccination rate would reduce the number of preventable cancers and the financial burden that treatment for these cases would create, the study found.

50% of treatments could have been avoided using the new tool, a UCLA-led study finds.

Q&A with the newly appointed director of cancer population genetics at UCLA’s Jonsson Comprehensive Cancer Center.

Combining biopsy strategies allowed doctors to find up to 33% more cancers.

The approach shows promise for extending the lives of people with a type of melanoma that contains a potent gene mutation, BRAF V600E.

“This trial was unique because it looks at younger women who haven’t gone through menopause,” said Dr. Sara Hurvitz, the study’s lead author.

“We can no longer look at this disease as one in which we should always be measuring survival in months,” said UCLA’s Dr. Edward Garon, the lead author.

The findings will both help identify women who are at highest risk of developing ovarian cancer and pave the way for identifying new therapies that can target these specific genes.

Research Brief: Researchers compared the system’s results with readings by UCLA doctors who had more than 10 years of experience.

“As our treatments become more technical and expensive, it is our responsibility to prove that these treatments lead to benefits that warrant the increased cost,” said UCLA’s Dr. Ann Raldow, the study's first author.

In a study with mice, using a technique called photothermal ablation enhanced the treatment’s effectiveness.

The findings answer questions that have been sought ever since 2005, when two Australian scientists won a Nobel Prize for their discovery of H. pylori and its role in gastric conditions.

The study could have implications for addressing value in the field of radiation medicine, a traditionally male-dominated specialty, according to UCLA's Dr. Luca Valle.

The findings stress the importance of learning how existing drugs work to repurpose them for potential use in treating other diseases.

UCLA’s Dr. Patricia Ganz is co-leading a new study to understand treatment tolerability by including the patient’s voice in cancer research.

Developed by UCLA scientists, the technique uses robots to simultaneously screen hundreds of different treatments.

“We now have a rational and logical way to develop immunotherapies going forward and a clinical development process for doing it,” said UCLA's Dr. Timothy Cloughesy.

A long-term, UCLA-led study finds that those with low- or intermediate-risk disease can safely cut treatment to four to five days.

A technique they developed coaxes pluripotent stem cells — which can can be grown indefinitely in the lab — into becoming mature T cells capable of killing tumor cells.

In this Q&A, Paul Boutros explains how scientists take cancer data, including DNA sequencing combined with clinical records, to design personal treatments.

The findings could lead to a better understanding of the metabolic needs of many different types of cancer.