genetics

An increase in the number and severity of heat waves over the coming years would pose a particular challenge for the species because small-bodied birds dehydrate more quickly.

Researchers led by UCLA’s Dr. Paul Krebsbach are the first to characterize the mechanism of the gene, and they found it regulates the molecular process that dictates cell growth and human development.

The discovery by UCLA geneticists could lead to new drugs to treat diabetes, obesity and heart disease.

The study, led by Professor Amander Clark, could lead to important advances in an area of medicine that historically has been underfunded and underappreciated.

The new method will improve the ability to identify genetic changes most likely to harm cells and contribute to disease.

The scientists are working on a way to stop heart disease in patients with this severe muscular dystrophy, which affects one in 5,000 male babies in the U.S.

The statistical analysis software the researchers have designed is more precise and reliable than previous methods.

The findings of this study could lead to the creation of new treatments for speech problems in people, including children with autism.

The UCLA-led study will help scientists better understand the debilitating condition.

The new method uses 'nanospears' to deliver genes directly to patient cells. Gene therapy has shown great promise as a treatment for a host of diseases, including hemophilia and certain types of cancer.

The five-year project funded by the National Institute of Allergy and Infectious Diseases will involve three projects to investigate factors that accelerate and prevent the re-emergence of HIV.

A UCLA-led study finds that the so-called “selfish” gene acts to remove cholesterol from blood vessels.

Their technique would enable an average biochemistry laboratory to make its own sequences for only about $2 per gene, far less than the $50 to $100 per gene commercial vendors charge.

A UCLA-led analysis identifies brain measures of major psychiatric disease. Researchers also pinpointed important differences in these disorders’ gene expression.

The scientists identified factors that can set the stage for disorders like schizophrenia, depression and ADHD that appear later in life.

UCLA geneticist Dr. Wayne Grody UCLA geneticist says many people are ill-equipped to handle troubling medical information without the guidance of physicians.

The research determined that many early symptoms of the disease can be completely corrected when the relevant genetic defect is turned off.

The process could help restore dystrophin, the protein missing in the muscles of boys with Duchenne muscular dystrophy.

The analysis had a 93 percent accuracy rate for forecasting the chance of survival in people with advanced cardiac disease.

The award from the John Templeton Foundation will help researchers address how much power individuals have over their own health.

The study suggests a new possible framework for treating people with familial hypercholesterolemia, an inherited condition characterized by extremely high levels of LDL, the so-called “bad cholesterol.”

UCLA researchers’ study using zebrafish shows how the disease turns a repair mechanism into one that damages nerve cells. The findings could lead to treatments to prevent nerve damage in leprosy and other diseases.

UCLA was among the first medical centers to use exome sequencing, which can analyze more than 20,000 genes at once.

An international team led by researchers from UCLA and Massachusetts General Hospital helped lead discovery of the first definitive genetic mutations.

UCLA researchers observed that mice with a form of autism had an inability to adapt to repeated whisker stimulation.