genetics

UCLA research findings show changes in same genes that clipped the sea bird’s wings cause human bone disorders.

Deletions or duplications of DNA along 22nd chromosome hint at biological underpinnings of these neuropsychiatric disorders.

The finding represents one of the clearest examples to date of the phenomenon — stretches of DNA that exist for no reason other than promoting their own inheritance — at the molecular level.

Adenosine deaminase-deficient severe combined immunodeficiency is a rare and life-threatening condition that can be fatal within the first year of life if left untreated.

The researchers identified genes that they believe control hundreds of other genes linked to Alzheimer’s disease, Parkinson’s disease, depression and several other disorders.

The device, developed by UCLA’s Aydogan Ozcan and colleagues in Sweden, could be manufactured for less than $500 each — far less expensive than the equipment that labs use for the same tests.

Neuroscientists at UCLA have developed a new technique for studying a particular type of cell in the brain known as an astrocyte that may play a role in diseases such as Lou Gehrig’s disease and Alzheimer's disease.

The findings could one day lead to improved therapies for people undergoing chemotherapy and radiation treatment for cancer.

A UCLA study used 3D chromosome-mapping technology to advance understanding of disorder’s cause. The work provides important new information about how schizophrenia originates and could lead to better treatments.

In a first-of-its-kind study, UCLA-led researchers have discovered a gene variant that could be a factor in determining which women experience the symptom.

The discovery opens up a new avenue of research into autism’s causes and potential therapies.

The technique involved amplifying a protein signal without using enzymes, which takes the process from two to four hours down to 10 minutes.

Scientists find new autism-linked gene, and discover that autistic siblings don’t always have the same disease-related mutations.

From the capuchin monkeys of Costa Rica to the Los Angeles area's mountain lions, UCLA experts are developing new techniques and advancing knowledge.

A team of scientists including researchers from UCLA has developed an RNA sequencing technique that could advance scientists’ use of stem cells in regenerative medicine.

A world-class scientist and educator, Kruglyak is a professor of human genetics and biological chemistry.

UCLA researchers pinpointed the function of a cluster of specialized genes that play a key role in creating and preserving hematopoietic stem cells and identified the process by which those genes are activated.

UCLA scientists have recently partnered with the Sandia National Laboratory to develop special screening libraries based on a gene-editing technology called CRISPR.

The researchers discovered good news as well: An omega-3 fatty acid known as docosahexaenoic acid seems to reverse the harmful changes.

The approach can help physicians identify disorders that may have gone undiagnosed for years. UCLA has been a leader in using the test since 2012.

Researchers also found an existing drug that can promote nerve regeneration in the central nervous system.

These changes could potentially lead to various developmental disorders and other health risks.

UCLA scientists’ finding could lead to new therapies for the disorder, which affects one in 68 children in the United States.

Archaeologist Matthew Curtis was part of a team that recently discovered a skeleton that yielded the first complete ancient genome ever found in Africa.

UCLA research reveals the three-dimensional atomic structure of a double-stranded RNA virus and the biological nano-switch that turns on transcription.